Pub. Date : 2009 Mar 13
PMID : 19168439
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | p66Shc links alpha(1)-ARs to an AKT signaling pathway that selectively phosphorylates/inactivates FOXO transcription factors and downregulates the ROS-scavenging protein manganese superoxide dismutase (MnSOD); the alpha(1)-AR-p66Shc-dependent pathway involving AKT does not regulate GSK3. | Reactive Oxygen Species | superoxide dismutase 2 | Homo sapiens |