Title : Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.

Pub. Date : 2009 Apr

PMID : 19164483






1 Functional Relationships(s)
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1 Xenopus oocytes expressing NH2-terminal-deleted hENT3 (expressed at the cell surface) showed pH-dependent interaction with several classes of nucleosides (anti-HIV ddNs, gemcitabine, fialuridine, ribavirin) that produce mitochondrial toxicity. gemcitabine solute carrier family 29 member 3 Homo sapiens