Pub. Date : 2009 Apr
PMID : 19164483
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Xenopus oocytes expressing NH2-terminal-deleted hENT3 (expressed at the cell surface) showed pH-dependent interaction with several classes of nucleosides (anti-HIV ddNs, gemcitabine, fialuridine, ribavirin) that produce mitochondrial toxicity. | Nucleosides | solute carrier family 29 member 3 | Homo sapiens |
| 2 | Transport studies in hENT3 gene-silenced JAR cells showed significant reduction in mitochondrial transport of nucleosides and nucleoside drugs. | Nucleosides | solute carrier family 29 member 3 | Homo sapiens |
| 3 | Transport studies in hENT3 gene-silenced JAR cells showed significant reduction in mitochondrial transport of nucleosides and nucleoside drugs. | Nucleosides | solute carrier family 29 member 3 | Homo sapiens |
| 4 | hENT3-mediated mitochondrial transport may play an important role in mediating clinically observed mitochondrial toxicity of nucleoside drugs. | Nucleosides | solute carrier family 29 member 3 | Homo sapiens |