Title : Peroxisome proliferator-activated receptor alpha and enzymes of carnitine biosynthesis in the liver are down-regulated during lactation in rats.

Pub. Date : 2009 Feb

PMID : 19154956






3 Functional Relationships(s)
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1 Peroxisome proliferator-activated receptor alpha and enzymes of carnitine biosynthesis in the liver are down-regulated during lactation in rats. Carnitine peroxisome proliferator activated receptor alpha Rattus norvegicus
2 In conclusion, the present study demonstrates for the first time that lactation leads to a down-regulation of PPARalpha and genes involved in hepatic carnitine synthesis and uptake of carnitine (OCTN1) in the liver, irrespective of litter size. Carnitine peroxisome proliferator activated receptor alpha Rattus norvegicus
3 In conclusion, the present study demonstrates for the first time that lactation leads to a down-regulation of PPARalpha and genes involved in hepatic carnitine synthesis and uptake of carnitine (OCTN1) in the liver, irrespective of litter size. Carnitine peroxisome proliferator activated receptor alpha Rattus norvegicus