Title : A G-protein gamma subunit mimic is a general antagonist of prion propagation in Saccharomyces cerevisiae.

Pub. Date : 2009 Jan 20

PMID : 19129493






1 Functional Relationships(s)
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1 Although the GPG1 gene is normally not expressed, over-expression of GPG1 inhibits propagation of not only [PSI(+)] but also [PIN(+)], [URE3] prions, and the toxic polyglutamine aggregate in S. cerevisiae. polyglutamine Gpg1p Saccharomyces cerevisiae S288C