Title : The proteolytic activity of insulin-degrading enzyme: a mass spectrometry study.

Pub. Date : 2009 May

PMID : 19127548






2 Functional Relationships(s)
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1 The roles that IDE/insulin concentration ratio, reaction time, adenosine 5"-triphosphate (ATP) and metal ions (Zn and Cu) have on the insulin cleavage pattern produced by IDE are investigated and a plausible interpretation involving the proteolytic action of the different IDE oligomeric forms is proposed. Adenosine Triphosphate insulin Homo sapiens
2 The roles that IDE/insulin concentration ratio, reaction time, adenosine 5"-triphosphate (ATP) and metal ions (Zn and Cu) have on the insulin cleavage pattern produced by IDE are investigated and a plausible interpretation involving the proteolytic action of the different IDE oligomeric forms is proposed. Adenosine Triphosphate insulin Homo sapiens