Title : Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells.

Pub. Date : 2009 Feb 14

PMID : 19121632






2 Functional Relationships(s)
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1 Chronic treatment (for 12 h) with EPA at lower concentrations (0.3-10 muM) increased the level of Kv1.5-FLAG protein as well as Kv1.5 channel current without changes in its gating kinetics, prolonging its half-life; in contrast, both EPA and DHA at higher concentrations (30-100 muM) decreased the expression of Kv1.5-FLAG. Eicosapentaenoic Acid latexin Homo sapiens
2 Chronic treatment (for 12 h) with EPA at lower concentrations (0.3-10 muM) increased the level of Kv1.5-FLAG protein as well as Kv1.5 channel current without changes in its gating kinetics, prolonging its half-life; in contrast, both EPA and DHA at higher concentrations (30-100 muM) decreased the expression of Kv1.5-FLAG. Eicosapentaenoic Acid latexin Homo sapiens