Pub. Date : 2008 Dec
PMID : 19120138
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Forced swimming, systemic interleukin-1beta (IL-1beta), and cholecystokinin (CCK) all activate brain stem noradrenergic cell groups, stimulate noradrenaline release in the PVN, and activate the HPA axis in nonpregnant rats. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |
2 | Forced swimming, systemic interleukin-1beta (IL-1beta), and cholecystokinin (CCK) all activate brain stem noradrenergic cell groups, stimulate noradrenaline release in the PVN, and activate the HPA axis in nonpregnant rats. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |
3 | HPA axis responses to IL-1beta and CCK can be reinstated in pregnant rats by systemic administration of the opioid receptor antagonist naloxone, and when infused directly into the PVN, naloxone restores noradrenaline release in the PVN following IL-1beta treatment. | Norepinephrine | interleukin 1 beta | Rattus norvegicus |