Title : Synthesis, transport and pharmacokinetics of 5'-amino acid ester prodrugs of 1-beta-D-arabinofuranosylcytosine.

Pub. Date : 2009 Jan-Feb

PMID : 19115956






1 Functional Relationships(s)
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1 Glycylsarcosine (gly-sar, a typical substrate of PepT1) uptake by Caco-2 cells can be inhibited by 2 in a concentration-dependent manner, and IC(50) for 2 was 2.18 +/- 0.12 mM. Glycine solute carrier family 15 member 1 Homo sapiens