Title : Antiinflammatory effects of etoricoxib alone and combined with NSAIDs in LPS-induced reactive arthritis.

Pub. Date : 2008 Dec

PMID : 19109739






2 Functional Relationships(s)
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1 Here, we compared etoricoxib, a specific COX-2 inhibitor, with other cyclooxygenase inhibitors on articular incapacitation, edema, leukocyte migration, and gastric damage, in a model of LPS-induced reactive arthritis in rats. Etoricoxib cytochrome c oxidase II, mitochondrial Rattus norvegicus
2 CONCLUSION: The present results suggest that the selective COX-2 inhibitor etoricoxib could be a better option than non-selective COX inhibitors, since it presented a potent inhibitory effect on the clinical signals and also a potent inhibition on cell migration. Etoricoxib cytochrome c oxidase II, mitochondrial Rattus norvegicus