Pub. Date : 2009 Jan 22
PMID : 19106084
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Clopidogrel requires transformation into an active metabolite by cytochrome P-450 (CYP) enzymes for its antiplatelet effect. | Clopidogrel | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | BACKGROUND: Clopidogrel requires transformation into an active metabolite by cytochrome P-450 (CYP) enzymes for its antiplatelet effect. | Clopidogrel | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 3 | METHODS: We tested the association between functional genetic variants in CYP genes, plasma concentrations of active drug metabolite, and platelet inhibition in response to clopidogrel in 162 healthy subjects. | Clopidogrel | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |