Title : Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase.

Pub. Date : 2009 Jan

PMID : 19105592






1 Functional Relationships(s)
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1 We found that human recombinant PGHS-2 catalyzed the oxidation of ortho (2",3"- and 3",4"-) and para (2",5"-) dihydroxy 4-chlorobiphenyl metabolites to their corresponding quinones. Quinones prostaglandin-endoperoxide synthase 2 Homo sapiens