Title : Redox thiol status plays a central role in the mobilization and metabolism of nitric oxide in human red blood cells.

Pub. Date : 2009 Mar

PMID : 19101643






2 Functional Relationships(s)
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1 We assessed the redox thiol status influence on nitric oxide (NO) metabolism and efflux in erythrocytes stimulated with acetylcholinesterase substrate (acetylcholine, ACh) and inhibitor (velnacrine maleate, VM). Sulfhydryl Compounds acetylcholinesterase (Cartwright blood group) Homo sapiens
2 We concluded that dithiothreitol-induced activation of erythrocyte thiol status decreases NO efflux and allows greater intracellular NO mobilization onto different derivative molecules, both in the absence and presence of acetylcholinesterase substrate and inhibitor. Sulfhydryl Compounds acetylcholinesterase (Cartwright blood group) Homo sapiens