Pub. Date : 2009 Jan 14
PMID : 19093868
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin exerts antidifferentiation effect through AMPKalpha-PPAR-gamma in 3T3-L1 adipocytes and antiproliferatory effect through AMPKalpha-COX-2 in cancer cells. | Curcumin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | Stimulation of AMPK by curcumin resulted in the down-regulation of PPAR (peroxisome proliferator-activated receptor)-gamma in 3T3-L1 adipocytes and the decrease in COX-2 in MCF-7 cells. | Curcumin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 3 | Regulation of AMPK and its downstream targets such as PPAR-gamma, Mapkinases, and COX-2 by curcumin appears to be important in controlling adipocytes and cancerous cells. | Curcumin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |