Pub. Date : 2009 Jan
PMID : 19084597
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Combining 2-ME(2) with eugenol (i) inhibited growth of prostate cancer cells and induced apoptosis at lower concentrations than either single agent alone; (ii) analysis of the data using combination index (CI) showed CI values of 0.4 indicating strong synergistic interaction; (iii) increased population of cells G(2)/M phase by 4.5-fold (p=0.01); (iv) significantly reduced expression of antiapoptotic protein Bcl-2 and enhanced expression of proapoptotic protein Bax. | Eugenol | BCL2 apoptosis regulator | Homo sapiens |