Title : Induction of COX-2 in human airway cells by manganese: role of PI3K/PKB, p38 MAPK, PKCs, Src, and glutathione depletion.

Pub. Date : 2009 Feb

PMID : 19084589






1 Functional Relationships(s)
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1 Importantly, the manganese-induced COX-2 expression was suppressed by treatment with the inhibitor of p38 MAPK (SB203580), PI3K/PKB (LY294002), PKCs (GO6983, GF109203X, Rottlerin), Src (PP1), or the thiol-containing compound (NAC). SB 203580 mitochondrially encoded cytochrome c oxidase II Homo sapiens