Title : Arsenite and its metabolites, MMA(III) and DMA(III), modify CYP3A4, PXR and RXR alpha expression in the small intestine of CYP3A4 transgenic mice.

Pub. Date : 2009 Sep 1

PMID : 19084030






2 Functional Relationships(s)
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1 The present study investigates the effect of sodium arsenite and its metabolites monomethylarsonous acid (MMA(III)) and dimethylarsinous acid (DMA(III)) on CYP3A4, PXR, and RXR alpha expression in the small intestine of CYP3A4 transgenic mice. monomethylarsonous acid cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 The present study investigates the effect of sodium arsenite and its metabolites monomethylarsonous acid (MMA(III)) and dimethylarsinous acid (DMA(III)) on CYP3A4, PXR, and RXR alpha expression in the small intestine of CYP3A4 transgenic mice. monomethylarsonous acid cytochrome P450 family 3 subfamily A member 4 Homo sapiens