Title : Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation.

Pub. Date : 2009 May-Jun

PMID : 19076306






1 Functional Relationships(s)
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1 In most of the regions examined, histone H3 acetylation peaked 24 h after UVR and then returned to baseline levels by 72 h. The induction of ATF3, COX2 and MKP1 was blocked in the presence of curcumin at doses that decrease in vivo histone H3 acetylation but not at lower doses that do not affect acetylation levels. Curcumin mitochondrially encoded cytochrome c oxidase II Homo sapiens