Title : Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts.

Pub. Date : 2009 Feb 6

PMID : 19074428






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A subset of BACE1 localizes to cholesterol-rich membrane microdomains, termed lipid rafts. Cholesterol beta-secretase 1 Homo sapiens
2 BACE1 processing in raft microdomains of cultured cells and neurons was characterized in previous studies by disrupting the integrity of lipid rafts by cholesterol depletion. Cholesterol beta-secretase 1 Homo sapiens