Title : Inhibition of human fetal brain acetylcholinesterase: marker effect of neurotoxicity.

Pub. Date : 1991 Jul

PMID : 1906943






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In general, organophosphates are more neurotoxic than carbamate compounds, as evidenced by higher degree of AChE inhibition by DFP and Metacid-50 as compared to eserine and carbaryl. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Assays were also done with psychotropic drugs by employing the procedure of in vitro AChE inhibition kinetics, and it was found that psychotropic drugs are less potent than organophosphate and carbamate compounds. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
3 Results indicate that pure and commercial organophosphates and carbamates and psychotropic drugs are all able to significantly alter the AChE activity. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens