Pub. Date : 2009 Jan
PMID : 19067746
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this study, the effect of different treatment regimens for MM on serum DKK-1 was evaluated and correlated with the response to treatment in 101 myeloma patients receiving bortezomib, thalidomide, lenalidomide, adriamycin and dexamethasone (AD) or high-dose chemotherapy (HDCT) followed by autologous stem cell transplantation (ASCT). | Lenalidomide | dickkopf WNT signaling pathway inhibitor 1 | Homo sapiens |
2 | A significant decrease of DKK-1 after therapy was seen in the following groups: Bortezomib (4059 pg/mL vs. 1862 pg/mL, P = 0.016), lenalidomide (11837 pg/mL vs. 4374 pg/mL, P = 0.039), AD (1668 pg/mL vs. 1241 pg/mL, P = 0.016), and AD + HDCT + ASCT (2446 pg/mL vs. 1082 pg/mL, P = 0.001). | Lenalidomide | dickkopf WNT signaling pathway inhibitor 1 | Homo sapiens |