Title : Unexpected link between anaphase promoting complex and the toxicity of expanded polyglutamines expressed in yeast.

Pub. Date : 2008 Dec 15

PMID : 19066445






1 Functional Relationships(s)
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1 We tested Cdh1 overexpression and the deletion of CLB2 (mitotic cyclin, substrate of APC/Cdh1) and found that both mutations had a rescuing effect on the expanded polyglutamine toxicity. polyglutamine Cdh1p Saccharomyces cerevisiae S288C