Title : DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family.

Pub. Date : 1991 Jul

PMID : 1906377






1 Functional Relationships(s)
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1 Non-transformed skin fibroblasts derived from five members of a cancer-prone family and three unrelated healthy volunteers were assayed for their levels of activity of the quinone reductase DT-diaphorase and for their sensitivity to the antitumor quinone mitomycin C (MMC). quinone NAD(P)H quinone dehydrogenase 1 Rattus norvegicus