Title : Effects of overexpression of huntingtin proteins on mitochondrial integrity.

Pub. Date : 2009 Feb 15

PMID : 19039036






1 Functional Relationships(s)
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1 In a Caenorhabditis elegans model of HD, we found that reduction of Drp-1 expression by RNA interference rescued the motility defect associated with the expression of Htt proteins with polyglutamine repeats. polyglutamine Dynamin GTPase Caenorhabditis elegans