Title : Cyclin A is essential for the p53-modulated inhibition from benzo(a)pyrene toxicity in A549 cells.

Pub. Date : 2009 Feb 4

PMID : 19027820






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclin A is essential for the p53-modulated inhibition from benzo(a)pyrene toxicity in A549 cells. Benzo(a)pyrene tumor protein p53 Homo sapiens
2 These results indicated that cyclin A is regulated by p53, not by B(a)P, and it is essential in the p53-modulated inhibition from benzo(a)pyrene toxicity in A549 cells, cyclin E and p21 also as downstream genes of p53 involved it, which is p27-independent. Benzo(a)pyrene tumor protein p53 Homo sapiens
3 These results indicated that cyclin A is regulated by p53, not by B(a)P, and it is essential in the p53-modulated inhibition from benzo(a)pyrene toxicity in A549 cells, cyclin E and p21 also as downstream genes of p53 involved it, which is p27-independent. Benzo(a)pyrene tumor protein p53 Homo sapiens