Title : Combined glutamine and arginine decrease proinflammatory cytokine production by biopsies from Crohn's patients in association with changes in nuclear factor-kappaB and p38 mitogen-activated protein kinase pathways.

Pub. Date : 2008 Dec

PMID : 19022976






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Arg(high)/Gln(high) decreased the production of TNFalpha, IL-1beta, IL-8, and IL-6 (each P < 0.01). Glutamine C-X-C motif chemokine ligand 8 Homo sapiens
2 Arg(low)/Gln(high) decreased IL-6 and IL-8 production (both P < 0.01), whereas Arg(high)/Gln(low) did not affect cytokine and NO production. Glutamine C-X-C motif chemokine ligand 8 Homo sapiens