Title : Ectopic cyclin D1 overexpression increases chemosensitivity but not cell proliferation in multiple myeloma.

Pub. Date : 2008 Dec

PMID : 19020753






1 Functional Relationships(s)
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1 Treatment with anti-myeloma drugs (melphalan, dexamethasone, bortezomib and immunomodulatory compounds) induced apoptosis earlier in D1 transfectants compared with RPMI8226 and mock control via the activation of both caspase-8 and -9. Melphalan caspase 8 Homo sapiens