Title : TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells.

Pub. Date : 2008 Dec

PMID : 19020730






3 Functional Relationships(s)
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1 TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells. TAE226 insulin like growth factor 1 receptor Homo sapiens
2 TAE226, a novel small molecule compound, is a potent ATP competitive inhibitor of FAK and IGF-IR. TAE226 insulin like growth factor 1 receptor Homo sapiens
3 TAE226 can block FAK and IGF-IR signaling pathways. TAE226 insulin like growth factor 1 receptor Homo sapiens