Pub. Date : 2009 Jan 16
PMID : 19019830
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Additionally, TRPM8 activity is sensitive to the phospholipid phosphoinositol 4,5-bisphosphate (PIP2), a substrate for the enzyme phospholipase C (PLC). | Phosphatidylinositol 4,5-Diphosphate | transient receptor potential cation channel subfamily M member 8 | Homo sapiens |
| 2 | These results suggest an adaptation model whereby TRPM8-mediated Ca2+ influx activates PLC, thereby decreasing PIP2 levels and resulting in reduced TRPM8 activity. | Phosphatidylinositol 4,5-Diphosphate | transient receptor potential cation channel subfamily M member 8 | Homo sapiens |