Pub. Date : 2009 Jan
PMID : 19015155
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damage. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 2 | Treatment of HCT116 p53(+/+) cells with the DNA-damaging agent oxaliplatin induced a p53-dependent transcriptional downregulation of dUTPase not observed in the isogenic null cell line. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 3 | Treatment of HCT116 p53(+/+) cells with the DNA-damaging agent oxaliplatin induced a p53-dependent transcriptional downregulation of dUTPase not observed in the isogenic null cell line. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 4 | Oxaliplatin treatment induced enrichment of p53 at the dUTPase promoter with a concomitant reduction in Sp1. | Oxaliplatin | tumor protein p53 | Homo sapiens |