Title : Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.

Pub. Date : 2009 Mar 25

PMID : 19013211






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Two members of the human aldo-keto reductase (AKR) superfamily participate in the biosynthesis of bile acids by catalyzing the NADP(H) dependent reduction of 3-keto groups (AKR1C4) and Delta4 double bonds (AKR1D1) of oxysterol precursors. NADP aldo-keto reductase family 1 member C4 Homo sapiens