Title : Haplotypic structure of ABCB1/MDR1 gene modifies the risk of the acute allograft rejection in renal transplant recipients.

Pub. Date : 2008 Nov 15

PMID : 19005401






1 Functional Relationships(s)
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1 BACKGROUND: Bioavailability of tacrolimus (Tac) and cyclosporine is determined by cytochrome P450IIIA and by P-glycoprotein encoded by the CYP3A4/CYP3A5 and ABCB1 genes. Cyclosporine cytochrome P450 family 3 subfamily A member 5 Homo sapiens