Title : Effects of capsaicin on human intestinal cell line Caco-2.

Pub. Date : 2001 Jul

PMID : 19003326






3 Functional Relationships(s)
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1 There was an increase in permeability at high concentration (200 to 500 muM) of capsaicin, and the effect was inhibited by pretreatment of capsazepine, which is a competitive antagonist of the vanilloid receptor 1 (VR1). Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens
2 There was an increase in permeability at high concentration (200 to 500 muM) of capsaicin, and the effect was inhibited by pretreatment of capsazepine, which is a competitive antagonist of the vanilloid receptor 1 (VR1). Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens
3 Our results showed that the permeability increase by capsaicin was through binding to VR1-like protein of Caco-2 cells. Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens