Title : Productivity enhancement of recombinant protein in CHO cells via specific promoter activation by oncogenes.

Pub. Date : 1999 Sep

PMID : 19003130






2 Functional Relationships(s)
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1 Furthermore, we found that hIL-6 production level of I13 was slightly improved by raising the CO(2) concentration from 5 to 8% possibly because of the enhanced growth rate. co(2) interleukin 6 Homo sapiens
2 However when cultured in 8% CO(2) condition, not only cell number, but also productivity increased significantly, resulted in great augmentation of hIL-6 production, maximum production being 88.6 mug/ml/3 days. co(2) interleukin 6 Homo sapiens