Pub. Date : 2009 Jan 15
PMID : 19001041
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RhoA activity decreased after 4 days simvastatin (P < 0.05); however, activity was no different from Control after 12 days. | Simvastatin | ras homolog family member A | Homo sapiens |
| 2 | Simvastatin down-regulated PI3k/Akt signalling, independently of RhoA, and up-regulated FOXO transcription factors and downstream gene targets known to be implicated in proteasomal- and lysosomal-mediated muscle proteolysis, carbohydrate oxidation, oxidative stress and inflammation in an in vivo model of statin-induced myopathy. | Simvastatin | ras homolog family member A | Homo sapiens |