Title : PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding.

Pub. Date : 2009 Jan

PMID : 18992768






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 PGRMC1 and its homologues regulate cholesterol synthesis by activating the P450 protein Cyp51/lanosterol demethylase, and the cholesterol synthetic pathway is an important target in cardiovascular disease and in treating infections. Cholesterol cytochrome P450 family 2 subfamily B member 6 Homo sapiens