Pub. Date : 1991 Jan
PMID : 1899225
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TNF induces c-fos via a novel pathway requiring conversion of arachidonic acid to a lipoxygenase metabolite. | Arachidonic Acid | tumor necrosis factor | Homo sapiens |
| 2 | We find that arachidonic acid, which is released in response to TNF, induces c-fos, but not c-jun mRNA in quiescent TA1 cells. | Arachidonic Acid | tumor necrosis factor | Homo sapiens |
| 3 | These data suggest that TNF activates two second messenger pathways, one of which is dependent on release of arachidonic acid and its subsequent conversion to a lipoxygenase metabolite. | Arachidonic Acid | tumor necrosis factor | Homo sapiens |