Pub. Date : 2008 Oct
PMID : 18991842
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | c-Fos is an intracellular regulator of cocaine-induced long-term changes. | Cocaine | FBJ osteosarcoma oncogene | Mus musculus |
| 2 | Using a genetically modified mouse in which Fos is primarily mutated in D1 receptor-bearing neurons in the brain, we examined a potential role of the immediate early gene Fos, which is rapidly induced by cocaine via D1 receptors, in mediating cocaine-induced persistent neurobiological changes. | Cocaine | FBJ osteosarcoma oncogene | Mus musculus |
| 3 | Using a genetically modified mouse in which Fos is primarily mutated in D1 receptor-bearing neurons in the brain, we examined a potential role of the immediate early gene Fos, which is rapidly induced by cocaine via D1 receptors, in mediating cocaine-induced persistent neurobiological changes. | Cocaine | FBJ osteosarcoma oncogene | Mus musculus |
| 4 | These findings suggest that c-Fos expressed in D1 receptor-bearing neurons mediates cocaine-induced persistent changes. | Cocaine | FBJ osteosarcoma oncogene | Mus musculus |