Title : Chaperonin chamber accelerates protein folding through passive action of preventing aggregation.

Pub. Date : 2008 Nov 11

PMID : 18987317






1 Functional Relationships(s)
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1 The original experiments reconstituting GroEL-GroES-mediated protein folding were carried out under "nonpermissive" conditions, where the chaperonin system was absolutely required and substrate proteins could not achieve the native state if diluted directly from denaturant into solution. denaturant heat shock protein family D (Hsp60) member 1 Homo sapiens