Title : Uncoupling of neurodegeneration and gliosis in a murine model of juvenile cortical lesion.

Pub. Date : 2009 May

PMID : 18985736






1 Functional Relationships(s)
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1 Whereas the total number of neurons and astrocytes in these brain regions remain unaltered, pointing to a non- gliotic neurodegeneration (as seen in schizophrenia), the subgroup of parvalbumin-positive inhibitory GABAergic interneurons is increased bilaterally in the hippocampus, as is the expression of the GABA-synthesizing enzyme GAD67. gamma-Aminobutyric Acid parvalbumin Mus musculus