Title : Non-synonymous sequence variants within the oxygen-dependent degradation domain of the HIF1A gene are not associated with pre-eclampsia in the Finnish population.

Pub. Date : 2008 Nov 3

PMID : 18980686






1 Functional Relationships(s)
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1 METHODS: Here we studied whether two single nucleotide sequence variants, c.1744 C>T that changes residue 582 of HIF-1alpha from proline to serine (P582S) and c.1762 G>A that changes residue 588 of HIF-1alpha from alanine to threonine (A588T) in the exon 12 of the HIF1A gene, are associated with pre-eclampsia. Proline hypoxia inducible factor 1 subunit alpha Homo sapiens