Pub. Date : 1991 Aug 1
PMID : 1898045
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Retinol bound to cellular retinol-binding protein (CRBP) or dispersed in solvent was esterified in a fatty acyl CoA-independent, PMSF-sensitive reaction, consistent with lecithin:retinol acyltransferase (LRAT) activity. | Vitamin A | lecithin retinol acyltransferase | Rattus norvegicus |
| 2 | Retinol bound to cellular retinol-binding protein (CRBP) or dispersed in solvent was esterified in a fatty acyl CoA-independent, PMSF-sensitive reaction, consistent with lecithin:retinol acyltransferase (LRAT) activity. | Vitamin A | lecithin retinol acyltransferase | Rattus norvegicus |
| 3 | LRAT activity exhibited the same Km (2 microM retinol) between tissues but a higher Vmax in liver as compared to that in mammary gland (47 vs 8 pmol/min/mg microsome protein, respectively). | Vitamin A | lecithin retinol acyltransferase | Rattus norvegicus |
| 4 | Thus, when substrate was near or below Km, retinol esterification occurred predominantly by LRAT in the liver and ARAT in the mammary gland, respectively. | Vitamin A | lecithin retinol acyltransferase | Rattus norvegicus |