Title : Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.

Pub. Date : 2008

PMID : 18946510






1 Functional Relationships(s)
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1 Results of enzyme kinetics revealed that curcumin, compared to the polyphenols quercetin, myricetin, kaempferol, luteolin and rutin, elicited a stronger competitive inhibitory effect on Glo1 (K(i) = 5.1+/-1.4 microM). Luteolin glyoxalase I Homo sapiens