Title : Novel piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.

Pub. Date : 2008 Nov 15

PMID : 18926711






1 Functional Relationships(s)
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1 In this report, we describe SAR in this series of compounds and show that the 3,4-methylenedioxybenzoyl (piperonyloyl) group on the nitrogen of piperidine and lipophilic substitution at the C(6)-position of pyrimidine are important for this inhibitory activity. piperidine sarcosine dehydrogenase Homo sapiens