Title : Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter.

Pub. Date : 2008 Dec

PMID : 18922886






4 Functional Relationships(s)
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1 The retinoic acids all-trans retinoic acid (AT-RA) and 9-cis retinoic acid (9C-RA) and the retinoic acid receptors RAR and RXR significantly induce transcriptional activity from a 200-bp PKD1 proximal promoter in transfected mammalian cells. Radium polycystin 1, transient receptor potential channel interacting Homo sapiens
2 The retinoic acids all-trans retinoic acid (AT-RA) and 9-cis retinoic acid (9C-RA) and the retinoic acid receptors RAR and RXR significantly induce transcriptional activity from a 200-bp PKD1 proximal promoter in transfected mammalian cells. Radium polycystin 1, transient receptor potential channel interacting Homo sapiens
3 RT-PCR showed that AT-RA treatment of HEK293T cells increased the levels of endogenous PKD1 RNA, and chromatin immunoprecipitation showed the presence of both RXR and Sp1 at the PKD1 proximal promoter. Radium polycystin 1, transient receptor potential channel interacting Homo sapiens
4 RT-PCR showed that AT-RA treatment of HEK293T cells increased the levels of endogenous PKD1 RNA, and chromatin immunoprecipitation showed the presence of both RXR and Sp1 at the PKD1 proximal promoter. Radium polycystin 1, transient receptor potential channel interacting Homo sapiens