Title : A potent anti-carcinoma and anti-acute myeloblastic leukemia agent, AG490.

Pub. Date : 2008 Oct

PMID : 18855573






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 The JAK-2 specific inhibitor, Tyrphostin AG490 is used to inhibit phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. Tyrphostins signal transducer and activator of transcription 3 Homo sapiens
2 The JAK-2 specific inhibitor, Tyrphostin AG490 is used to inhibit phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. Tyrphostins signal transducer and activator of transcription 3 Homo sapiens