Pub. Date : 2008 Nov 7
PMID : 18854902
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These studies indicated that only Co(II) complexed with glycylglycylhistidine (GGH) induced DNA strand breaks at low sulfite concentrations (1-80 microM) via strong oxidants formed in the reaction. | Sulfites | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | In the presence of the other complexes, some damage occurred only in the presence of high sulfite concentrations (0.1-2.0 mM) after incubation for 4 h. In the presence of GGH, Co(II) and dissolved O2, DNA damage must involve a reactive high-valent cobalt complex. | Sulfites | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |