Pub. Date : 2008 Oct 21
PMID : 18854824
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP2C19 is a drug-metabolising enzyme involved in the metabolism of a number of chemotherapeutic agents including cyclophosphamide. | Cyclophosphamide | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |
| 2 | There is increasing interest in using pharmacogenetics to "individualise medicine", however, the results of this study indicate that in a cancer population genotyping for CYP2C19 would significantly underestimate the number of phenotypic PM of drugs, such as cyclophosphamide, which may be metabolised by this enzyme. | Cyclophosphamide | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |