Title : Expression and characterization of CYP51, the ancient sterol 14-demethylase activity for cytochromes P450 (CYP), in the white-rot fungus Phanerochaete chrysosporium.

Pub. Date : 2008 Dec

PMID : 18853217






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CYP51 was cloned from a cDNA library and expressed in both Escherichia coli, where it exhibited high affinity for azole antifungals, and Saccharomyces cerevisiae. Azoles sterol 14-demethylase Saccharomyces cerevisiae S288C
2 The CYP51 protein exhibited high affinity (k (d) 0.25-0.45 microM) for azole antifungal compounds. Azoles sterol 14-demethylase Saccharomyces cerevisiae S288C