Title : Heat shock protein induction in rat pancreatic islets by recombinant human interleukin 1 beta.

Pub. Date : 1991 Mar

PMID : 1884886






1 Functional Relationships(s)
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1 Since cytotoxicity induced by free radicals and by heat may activate the same cellular repair mechanism (the heat shock response), the aim of this study was to investigate the pattern of protein synthesis in isolated islets after exposure to interleukin 1 beta (150 pg/ml, 24 h), tumour necrosis factor alpha (50 ng/ml, 24 h) heat shock (43 degrees C, 30 min) and H2O2 (0.1 mmol/l, 20 min). Hydrogen Peroxide interleukin 1 beta Rattus norvegicus